Page 14 - ESGO - Vulvar cancer - Complete report_fxd2
P. 14

Table 1. Staging systems of squamous cell vulvar cancer

PRIMARY TUMOUR T

TNM categories5  FIGO stages6  Definition

TX               IA            Primary tumour cannot be assessed
T0               IB            No evidence of primary tumour
Tis*             II            Carcinoma in situ
T1a                            Lesions ≤ 2 cm in size, confined to the vulva or perineum and with stromal invasion ≤ 1.0 mm**, no nodal metastasis
T1b                            Lesions > 2 cm in size or with stromal invasion > 1.0 mm*, confined to the vulva or perineum, with negative nodes
T2***                          Tumour of any size with extension to adjacent perineal structures 1/3 lower urethra, 1/3 lower vagina, anus with
                               negative nodes
T3****           IVA           Tumour invades upper urethral and/or vaginal mucosa, bladder mucosa, rectal mucosa, or fixed to pelvic bone

REGIONAL LYMPH NODES N

TNM categories5 FIGO stages6   Definition

NX               IIIA          Regional lymph nodes cannot be assessed
N0               IIIA          No regional lymph node metastasis
N1               IIIB          One or two regional lymph nodes with the following features
 N1a            IIIB          One or two node metastasises, each 5 mm or less
 N1b            IIIB          One lymph node metastasis 5 mm or greater
N2               IIIC          Regional lymp node metastasis with the following features
 N2a            IVA           Three or more lymph node metastases each less than 5 mm
 N2b                          Two or more lymph node metastases 5 mm or greater
 N2c                          Lymph node metastasis with extracapsular spread
N3                             Fixed or ulcerated regional lymph nodes

DISTANT METASTASIS M

TNM categories5  FIGO stages6  Definition
                 IVB
*                              No distant metastasis
                               Distant metastasis incluing pelvic lymph node metastasis
M0

M1

* FIGO no longer includes stage 0 Tis, ** the depth of invasion is defined as the measurement of the tumour from the epithelial-stromal junction of the adjacent
most superficial dermal papilla to the deepest point of invasion, *** FIGO uses the classification T2/T3. This is defined as T2 in TNM, **** FIGO uses the
classification T4. This is defined as T3 in TNM.

                                VULVAR CANCER - GUIDELINES 
                                                      14
   9   10   11   12   13   14   15   16   17   18   19