Page 23 - Ovarian Cancer Surgery - Quality Indicators
P. 23

Table 7. Original studies evaluating the impact of physician specialty on survival

Authorreference                Year FIGO Specialties                      N Survival analysis

                                     stage                                             HR 95% CI       p-value Type of analysis

Overall survival               1993  I OB/GYN reference vs. GS            907 vs. 279  1.26 0.84-1.90  > 0.05    univariate
    Nguyen et al.238,a,b       1993                                       907 vs. 191  1.06 0.63-1.78  > 0.05    univariate
    Nguyen et al.238,a,b       1993  I OB/GYN reference vs. GYO           274 vs. 97   1.65 1.17-2.32  ≤ 0.05    univariate
    Nguyen et al.238,a,b       1993                                       274 vs. 77   0.88 0.57-1.36  > 0.05    univariate
    Nguyen et al.238,a,b       1999  II OB/GYN reference vs. GS           318 vs. 24   1.01 0.40-2.57  > 0.05    multivariate
    Junor et al.229,a,b        1999                                       318 vs. 68   0.83 0.45-1.55  > 0.05    multivariate
    Junor et al.229,a,b        1999  II OB/GYN reference vs. GYO          119 vs. 12   0.67 0.25-1.75  > 0.05    multivariate
    Junor et al.229,a,b        1999                                       119 vs. 32   1.00 0.56-1.80  > 0.05    multivariate
    Junor et al.229,a,b        2002  I OB/GYN reference vs. GS            79 vs. 17    3.57 1.41-9.02  ≤ 0.05    multivariate
    Grossi et al.231,a         2002                                       79 vs. 60    1.58 0.60-4.17  > 0.05    multivariate
    Grossi et al.231,a         2006  I OB/GYN reference vs. GYO           409 vs. 144  1.21 0.93-1.59  0.160     multivariate
    Earle et al.234,a          2006                                       409 vs. 198  0.97 0.75-1.24  0.788     multivariate
    Earle et al.234,a          2006  II OB/GYN reference vs. GS           135 vs. 64   0.50 0.26-0.94  0.03      univariate
    Engelen et al.233,a        1992                                       21 vs. 26    0.52 0.22-1.23  < 0.05c   univariate
    Mayer et al.246,a,b        1997  II OB/GYN reference vs. G YO         25 vs. 29    0.25 0.07-0.94  0.04      univariate
    Puls et al.247,a,b         2002                                       195 vs. 124  1.29 0.69-2.39  0.421     univariate
    Carney et al.230,a,b       2007  I-II OB/GYN reference vs. GS         211 vs. 100  0.77 0.53-1.12  0.157     univariate
    Chan et al.240,a           2008                                       485 vs. 664  1.00 0.86-1.16  > 0.05    multivariate
    Elit et al.217             2008  I-II OB/GYN reference vs. G YO       485 vs. 158  1.19 0.94-1.50  > 0.05    multivariate
    Elit et al.217             2008                                       485 vs. 15   1.52 1.18-1.95  < 0.05    multivariate
    Elit et al.217             1993  I-II OB/GYN reference vs. G S        656 vs. 382  1.32 1.18-1.48  ≤ 0.05    univariate
    Nguyen et al.238,a         1993                                       656 vs. 317  1.06 0.94-1.20  > 0.05    univariate
    Nguyen et al.238,a         1999  I-II OB/GYN reference vs. G YO       454 vs. 151  1.32 1.07-1.63  0.009     multivariate
    Junor et al.229,a,d        1999                                       454 vs. 192  0.75 0.62-0.92  0.005     multivariate
    Junor et al.229,a,d        2006  I-II OB/GYN reference vs. GYO        99 vs. 24    1.68 0.74-3.79  0.220     multivariate
    Paulsen et al.237,a,d      2006                                       99 vs. 75    0.47 0.25-0.87  0.017     multivariate
    Paulsen et al.237,a,d      2010  I-II Other reference vs. GYO         NA           1.63 1.56-1.71  < 0.0001  multivariate
    Mercado et al.215          2010                                       NA           1.56 1.52-1.61  < 0.0001  multivariate
    Mercado et al.215          2002  I Other reference vs. GYO            65 vs. 44    NA NA           > 0.05    multivariate
    Grossi et al.231,a,d       2002                                       65 vs. 142   NA NA           > 0.05    multivariate
    Grossi et al.231,a,d       2006  I-II Other reference vs. GYO         968 vs. 529  1.16 1.04-1.30  0.010     multivariate
    Earle et al.234,a,d        2006                                       968 vs. 819  0.99 0.89-1.09  0.833     multivariate
    Earle et al.234,a,d        2007  IC-II   Other reference vs. GYO      232 vs. 53   1.25 0.92-1.71  0.158     multivariate
    Skirnisdottir et al.239,a  2007                                       232 vs. 137  1.03 0.83-1.30  0.772     multivariate
    Skirnisdottir et al.239,a  2006  I-IV GYO reference vs. OB/GYN        191 vs. 119  0.75 0.58-0.96  0.02      univariate
    Engelen et al.233,a,d      2002                                       243 vs. 172  0.69 0.54-0.87  0.002     univariate
    Carney et al.230,a,d       2006  I-IV GYO reference vs. GS            145 vs. 216  0.98 0.74-1.31  0.911     multivariate
    Bailey et al.242,a         2007                                       692 vs. 398  0.77 0.67-0.88  < 0.001   univariate
    Chan et al.240,a           1992  I-IV GYO reference vs. Other         129 vs. 121  0.53 0.39-0.71  < 0.001   univariate
    Eisenkop et al.241,a       1993                                       473 vs. 429  1.22 1.09-1.36  ≤ 0.05    univariate
    Nguyen et al.238,a         1993  III OB/GYN reference vs. GS          473 vs. 178  1.12 0.97-1.30  > 0.05    univariate
    Nguyen et al.238,a         1999                                       134 vs. 23   1.26 0.78-2.04  > 0.05    multivariate
    Junor et al.229,a,d        1999  III OB/GYN reference vs. GYO         134 vs. 54   1.01 0.71-1.45  > 0.05    multivariate
    Junor et al.229,a,d
                                     III OB/GYN reference vs. GS

                                     III OB/GYN reference vs. GYO

                                     IIIC OB/GYN reference vs. GS

                                     IIIC OB/GYN reference vs. GYO

                                     IIIC-IV GYO/GYN reference vs. GS

                                     IIIC-IV GYO/GYN reference vs. Other

                                     III-IV OB/GYN reference vs. GS

                                     III-IV OB/GYN reference vs. GYO

                                     III-IV  OB/GYN reference vs. GS

                                     III-IV  OB/GYN reference vs. GYO

                                     III-IV  OB/GYN reference vs. GS

                                     III-IV  OB/GYN reference vs. GYO

                                     III-IV  OB/GYN reference vs. GYO

                                     III-IV  Other reference vs. GYO

                                     III-IV  Other reference vs. GYO

                                     III-IV  Other reference vs. GYO

                                     IIIC-IVA Other reference vs. GYO

                                     IV OB/GYN reference vs. GS

                                     IV OB/GYN reference vs. GYO

                                     IV OB/GYN reference vs. GS

                                     IV OB/GYN reference vs. GYO

a study included in the systematic review published by du Bois et al.209, b study included in the systematic review published by Giede et al.248, c the authors stated that

the specialty of the surgeon attained statistical significance for survival p < 0.05) in the Cox regression analysis, but details were not reported. Thus, the presented
numbers were estimated from the published survival curves. The upper limit of the confidence interval does not correspond with the reported p-value of p < 0.05, d
study included in the systematic review published by Vernooij et al. 2007) 228, CI confidence interval, GS general surgeon, GYO gynecologic oncologist, HR hazard

ratio, OB/GYN obstetrician/general gynecologist, NA data not available.

                                              OVARIAN CANCER SURGERY - QUALITY INDICATORS 
                                                                                    23
   18   19   20   21   22   23   24   25   26   27   28