Page 24 - Ovarian Cancer Surgery - Quality Indicators
P. 24

Original studies evaluating the impact of physician specialty on survival continued

Authorreference                  Year FIGO Specialties                      N                   Survival analysis
                                                                                                HR 95% CI
                                       stage                                                                       p-value Type of analysis

Disease-free survival            2009  I-IV       GYO reference vs. GYN     98 vs. 136          0.861 0.573-1.295 0.473 multivariate
    Kumpulainen et al.178                         GYO reference vs. GYN     102 vs. 136

5-year ovarian cancer specific mortality

Kumpulainen et al.178            2009  I-IV                                                     1.237 0.752-2.03 0.403 multivariate

CI confidence interval, GYO gynecologic oncologist, GYN general gynecologist, HR hazard ratio.

Table 8. Original studies evaluating the impact of physician specialty on surgical outcome

Authorreference                  Year     FIGO    Specialties               N Survival analysis
                                          stage
                                                                                                HR 95% CI          p-value Type of analysis

No residual tumour               2006     III     OB/GYN reference vs. GYO  142 vs. 98          2.45 1.20-5.01     0.014  univariate
                                 2006     III     OB/GYN reference vs. GYO  92 vs. 53           3.40 1.51-7.65     0.003  univariate
    Engelen et al.233,a,b,c      2006     IIIC    OB/GYN reference vs. GS   99 vs. 24           1.17 0.41, 3.30    0.771  univariate
    Kumpulainen et al.236,a,b,d  2006     IIIC    OB/GYN reference vs. GYO  99 vs. 75           1.19 0.59-2.40     0.632  univariate
    Paulsen et al.237,a,b,d      2007     III-IV  OB/GYN reference vs. GS   233 vs. 46          0.14 0.00-0.83     0.026  univariate
    Paulsen et al.237,a,b,d      2007     III-IV  OB/GYN reference vs. GYO  233 vs. 137         1.12 0.56-2.23     0.742  univariate
    Skirnisdottir et al.239,a,c
    Skirnisdottir et al.239,a,c

Residual tumour ≤ 1 mm           1992 IIIC-IVA Other reference vs. GYO      137 vs. 126 10.86 6.06-19.45 < 0.001 univariate
    Eisenkop et al.241,a,c

Residual tumour ≤ 2 mm           1992     IIB-IV  OB/GYN reference vs. GS   14 vs. 13           0.06 0.01-0.62     0.018  univariate
                                 2006     III     OB/GYN reference vs. GYO  92 vs. 53           1.36 0.69-2.69     0.373  univariate
    Grant et al.245,a,c
    Kumpulainen et al.236,a,b,d

Residual tumour < 20 mm          1999     III     OB/GYN reference vs. GS   432 vs. 146         0.33 0.19-0.57     < 0.001 univariate
                                 2006     III     OB/GYN reference vs. GYO  277 vs. 163         1.30 0.87-1.93     0.198 univariate
    Junor et al.229,a,b,c        2001     III-IV  OB/GYN reference vs. GS   148 vs. 5           0.30 0.03-2.77     0.290 univariate
    Engelen et al.233,a,b,c      2002     III-IV  OB/GYN reference vs. GS   65 vs. 44           0.41 0.16-1.02     0.055 univariate
    Olaitan et al.224,a,b,d      2007     III-IV  OB/GYN reference vs. GS   233 vs. 46          0.12 0.03-0.50     0.004 univariate
    Grossi et al.231,a,b,c       2007     III-IV  OB/GYN reference vs. GYO  233 vs. 137         1.44 0.92-2.26     0.114 univariate
    Skirnisdottir et al.239,a,c
    Skirnisdottir et al.239,a,c

Debulking > 95 % and residual tumour < 15 mm

Chen et al.244,a,c               1985 III-IV      OB/GYN ref erence vs. GYO 37 vs. 47           75.57 9.35-610.74 < 0.001 univariate

a study included in the systematic review published by du Bois et al. 2009) 209, b study included in the systematic review published by Vernooij et al. 2007) 228, c
retrospective study, d prospective study, CI confidence interval, GS general surgeon, GYO gynecologic oncologist, HR hazard ratio, OB/GYN obstetrician/general

gynecologist, NA data not available.

                                                   OVARIAN CANCER SURGERY - QUALITY INDICATORS 
                                                                                         24
   19   20   21   22   23   24   25   26   27   28   29